Digital PCR Discriminates between SARS-CoV-2 Omicron Variants and Immune Escape Mutations

Digital PCR Discriminates between SARS-CoV-2 Omicron Variants and Immune Escape Mutations

ABSTRACT As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve, mutations arise that will allow the virus to evade immune defenses and therapeutics. Assays that can identify these mutations can be used to guide personalized patient treatment plans. Digital PCR (dPCR) is...

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Bibliographic Details
Main Authors: Steven C. Holland, LaRinda A. Holland, Matthew F. Smith, Mihyun B. Lee, James C. Hu, Efrem S. Lim
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
digital PCR
monoclonal antibody
immune escape mutations
clinical diagnostics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05258-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05258-22

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