Stimulus-responsive assembly of nonviral nucleocapsids

Abstract Controlled assembly of a protein shell around a viral genome is a key step in the life cycle of many viruses. Here we report a strategy for regulating the co-assembly of nonviral proteins and nucleic acids into highly ordered nucleocapsids in vitro. By fusing maltose binding protein to the...

Full description

Bibliographic Details
Main Authors: Mao Hori, Angela Steinauer, Stephan Tetter, Jamiro Hälg, Eva-Maria Manz, Donald Hilvert
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47808-1