The impact of long-acting muscarinic antagonists on mucus hypersecretion and cough in chronic obstructive pulmonary disease: a systematic review

Patients suffering from chronic obstructive pulmonary disease (COPD) clinically manifest airway mucus hypersecretion as sputum expectoration and cough. Evidence accumulated in the past decade has shown that the cholinergic system not only regulates airway smooth muscle contraction but also the activ...

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Bibliographic Details
Main Authors: Luigino Calzetta, Beatrice Ludovica Ritondo, Maria Cristina Zappa, Gian Marco Manzetti, Andrea Perduno, Janis Shute, Paola Rogliani
Format: Article
Language:English
Published: European Respiratory Society 2022-05-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/31/164/210196.full