Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment.

Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment.

The epididymis maintains a state of immune tolerance towards spermatozoa while also protecting them and itself against infection and acute inflammation. The immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (Ido1) participates in this delicate local equilibrium. Using the mouse Ido1(-/-) model,...

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Bibliographic Details
Main Authors: Aicha Jrad-Lamine, Joelle Henry-Berger, Christelle Damon-Soubeyrand, Fabrice Saez, Ayhan Kocer, Laurent Janny, Hanae Pons-Rejraji, David H Munn, Andrew L Mellor, Najoua Gharbi, Rémi Cadet, Rachel Guiton, Robert J Aitken, Joël R Drevet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688773?pdf=render

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http://europepmc.org/articles/PMC3688773?pdf=render

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