A combination of pre-infusion serum ferritin, CRP and IL-6 predicts outcome in relapsed/refractory multiple myeloma patients treated with CAR-T cells

A combination of pre-infusion serum ferritin, CRP and IL-6 predicts outcome in relapsed/refractory multiple myeloma patients treated with CAR-T cells

BackgroundChimeric antigen receptor - T (CAR-T) cell therapy has shown remarkable efficacy in patients with relapsed/refractory multiple myeloma (R/R MM). However, a subset of patients still experienced progression or relapse, and the predictors of prognosis are little known. We analyzed the inflamm...

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Bibliographic Details
Main Authors: Yang Liu, Xingxing Jie, Li Nian, Ying Wang, Congyue Wang, Jin Ma, Jingjing Jiang, Qingyun Wu, Jianlin Qiao, Wei Chen, Jiang Cao, Zhiling Yan, Ming Shi, Hai Cheng, Feng Zhu, Wei Sang, Depeng Li, Chong Chen, Kailin Xu, Zhenyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
chimeric antigen receptor T cell
relapsed/refractory
multiple myeloma
prognostic predictor
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1169071/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1169071/full

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