Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans

Introduction: Pathogenic Leptospira is the causative agent of leptospirosis, a widely disseminated disease of human and veterinary concern. The development of vaccines that elicit cross-protective immunity through multiple leptospiral serovars has long been pursued. The aim of this study was to deve...

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Bibliographic Details
Main Authors: Luis G.V. Fernandes, Aline F. Teixeira, Antonio F.S. Filho, Gisele O. Souza, Silvio A. Vasconcellos, Marcos B. Heinemann, Eliete C. Romero, Ana L.T.O. Nascimento
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217300358