Synthesis, Evaluation of Vasorelaxant Activity, and Molecular Docking of Pyranopyrazole Derivatives as Calcium Channel Blockers

Pyranopyrazole analogs are novel synthetic compounds with many biological activities. In this research,we synthesized six new pyranopyrazole derivatives using a biocompatible catalyst and evaluated their vasorelaxant and calcium channel binding properties in isolated rat thoracic aorta. Male Sprague...

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Bibliographic Details
Main Authors: Saghar Mowlazadeh Haghighi, Mohammad Fathalipour, Maryam Abbasi, Azar Purkhosrow, Somayeh Oftadehgan, Ali Khalafi-Nezhad, Elahe Sattarinezhad
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-06-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Online Access:https://tips.sums.ac.ir/article_49338_c06df215e91c57d1b589966d04570bad.pdf