IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection.
Type 2 immune responses are essential in protection against intestinal helminth infections. In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti-helminth immunity. After infection with Nippostrongy...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3795034?pdf=render |