Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a significant amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA), European Medicines Agency (EMA), or Worldwide for another indicatio...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Sergey Shityakov, Ekaterina V. Skorb, Carola Y. Förster, Thomas Dandekar
التنسيق:	مقال
اللغة:	English
منشور في:	Frontiers Media S.A. 2021-10-01
سلاسل:	Frontiers in Chemistry
الموضوعات:	scaffold search approved drugs drug repurposing alzheimer's disease chemical similarity molecular modeling
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fchem.2021.736509/full

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