Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a significant amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA), European Medicines Agency (EMA), or Worldwide for another indicatio...

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Bibliografiska uppgifter
Huvudupphovsmän:	Sergey Shityakov, Ekaterina V. Skorb, Carola Y. Förster, Thomas Dandekar
Materialtyp:	Artikel
Språk:	English
Publicerad:	Frontiers Media S.A. 2021-10-01
Serie:	Frontiers in Chemistry
Ämnen:	scaffold search approved drugs drug repurposing alzheimer's disease chemical similarity molecular modeling
Länkar:	https://www.frontiersin.org/articles/10.3389/fchem.2021.736509/full

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