Amino acid modified OCMC-g-Suc-β-CD nanohydrogels carrying lapatinib and ginsenoside Rg1 exhibit high anticancer activity in a zebrafish model

Amino acid modified OCMC-g-Suc-β-CD nanohydrogels carrying lapatinib and ginsenoside Rg1 exhibit high anticancer activity in a zebrafish model

Nanohydrogels show great potential as efficient drug carriers due to their biocompatibility, low toxicity, and high water absorbability. In this paper, we prepared two O-carboxymethylated chitosan (OCMC)-based polymers functionalized with β-cyclodextrin (β-CD) and amino acid. The structures of the p...

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Bibliographic Details
Main Authors: Li Cui, Xiaolan Liu, Rongjun Yan, Qixu Chen, Lizhen Wang, Shah Nawaz, Dawei Qin, Daijie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
OCMC-g-β-CD nanohydrogels
lapatinib
ginsenoside Rg1
anticancer activity
zebrafish
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1149191/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1149191/full

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