Quantifying the contribution of Neanderthal introgression to the heritability of complex traits

We lack a comprehensive understanding of how Neanderthal ancestry influences human traits. This study finds that regions with Neanderthal ancestry are broadly depleted of trait-associated variation; yet, introgressed variants likely contributed to human adaptation in a few traits, like skin color an...

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Bibliographic Details
Main Authors: Evonne McArthur, David C. Rinker, John A. Capra
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24582-y