HPLC and SFC Enantioseparation of (±)-<i>Trans</i>-β-Lactam Ureas on Immobilized Polysaccharide-Based Chiral Stationary Phases—The Introduction of Dimethyl Carbonate as an Organic Modifier in SFC

HPLC and SFC Enantioseparation of (±)-<i>Trans</i>-β-Lactam Ureas on Immobilized Polysaccharide-Based Chiral Stationary Phases—The Introduction of Dimethyl Carbonate as an Organic Modifier in SFC

A series of nine racemic <i>trans</i>-β-lactam ureas were analyzed for enantiomer separation by high-performance liquid chromatography (HPLC) and supercritical fluid chromatography (SFC). The separations were performed on three immobilized polysaccharide-based chiral analytical columns (...

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Bibliographic Details
Main Authors: Mladenka Jurin, Darko Kontrec, Marin Roje
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Separations
Subjects:
<i>trans</i>-β-lactam ureas
enantioseparation
chiral chromatography
high-performance liquid chromatography (HPLC)
supercritical fluid chromatography (SFC)
dimethyl carbonate (DMC)
Online Access:https://www.mdpi.com/2297-8739/11/2/38

Internet

https://www.mdpi.com/2297-8739/11/2/38

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