The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes

Abstract Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta (β) globin chain. The HBB*S gene is in linkage disequilibrium with five main haplotypes in the β-globin-like gene cluster named according to their ethnic and geographic origins: Bantu (CAR), Beni...

Full description

Bibliographic Details
Main Authors: Juliana D. Lindenau, Sandrine C. Wagner, Simone M. de Castro, Mara H. Hutz
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400515&lng=en&tlng=en