The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes

The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes

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Abstract Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta (β) globin chain. The HBB*S gene is in linkage disequilibrium with five main haplotypes in the β-globin-like gene cluster named according to their ethnic and geographic origins: Bantu (CAR), Beni...

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Bibliographic Details
Main Authors:	Juliana D. Lindenau, Sandrine C. Wagner, Simone M. de Castro, Mara H. Hutz
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Genética
Series:	Genetics and Molecular Biology
Subjects:	βS globin haplotypes sickle cell disease Hemoglobin S migration
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400515&lng=en&tlng=en

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