Targeting Autophagy for Developing New Therapeutic Strategy in Intervertebral Disc Degeneration

Targeting Autophagy for Developing New Therapeutic Strategy in Intervertebral Disc Degeneration

Intervertebral disc degeneration (IVDD) is a prevalent cause of low back pain. IVDD is characterized by abnormal expression of extracellular matrix components such as collagen and aggrecan. In addition, it results in dysfunctional growth, senescence, and death of intervertebral cells. The biological...

Full description

Bibliographic Details
Main Authors: Md Entaz Bahar, Jin Seok Hwang, Mahmoud Ahmed, Trang Huyen Lai, Trang Minh Pham, Omar Elashkar, Kazi-Marjahan Akter, Dong-Hee Kim, Jinsung Yang, Deok Ryong Kim
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
intervertebral disc degeneration
autophagy
low back pain
autophagy-targeting compounds
ECM degradation
Online Access:https://www.mdpi.com/2076-3921/11/8/1571

Internet

https://www.mdpi.com/2076-3921/11/8/1571

Similar Items