A network model for the specification of vulval precursor cells and cell fusion control in Caenorhabditis elegans

The vulva of Caenorhabditis elegans has been long used as an experimental model of cell differentiation and organogenesis. While it is known that the signaling cascades of Wnt, Ras/MAPK and NOTCH interact to form a molecular network, there is no consensus regarding its precise topology and dynamical...

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Bibliographic Details
Main Authors: Nathan eWeinstein, Luis eMendoza
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00112/full