Work-Up and Treatment Strategies for Individuals with <i>PIK3CA</i>-Related Disorders: A Consensus of Experts from the Scientific Committee of the Italian Macrodactyly and PROS Association

Work-Up and Treatment Strategies for Individuals with <i>PIK3CA</i>-Related Disorders: A Consensus of Experts from the Scientific Committee of the Italian Macrodactyly and PROS Association

<i>PIK3CA</i>-related disorders encompass many rare and ultra-rare conditions caused by somatic genetic variants that hyperactivate the PI3K-AKT-mTOR signaling pathway, which is essential for cell cycle control. <i>PIK3CA</i>-related disorders include <i>PIK3CA</i>...

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Bibliographic Details
Main Authors: Andrea Gazzin, Chiara Leoni, Germana Viscogliosi, Federica Borgini, Lucrezia Perri, Matteo Iacoviello, Marilidia Piglionica, Maurizio De Pellegrin, Giovanni Battista Ferrero, Andrea Bartuli, Giuseppe Zampino, Paola Sabrina Buonuomo, Nicoletta Resta, Alessandro Mussa
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Genes
Subjects:
<i>PIK3CA</i>
PI3K/AKT/mTOR
overgrowth
<i>PIK3CA</i>-related overgrowth spectrum
personalized medicine
repurposed drugs
Online Access:https://www.mdpi.com/2073-4425/14/12/2134

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https://www.mdpi.com/2073-4425/14/12/2134

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