Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications

Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications

Polyamines participate in the processes of cell growth and development. The degradation branch of their metabolism involves amine oxidases. The oxidation of spermine, spermidine and putrescine releases hydrogen peroxide and the corresponding aminoaldehyde. Polyamine-derived aminoaldehydes have been...

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Bibliographic Details
Main Authors: Marek Šebela, Michaela Rašková
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
acrolein
aldehyde dehydrogenase
amine oxidase
aminoaldehyde
3-aminopropanal
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/28/21/7429

Internet

https://www.mdpi.com/1420-3049/28/21/7429

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