Neuropathological features of levodopa-responsive parkinsonism in multiple system atrophy: an autopsy case report and comparative neuropathological study

Neuropathological features of levodopa-responsive parkinsonism in multiple system atrophy: an autopsy case report and comparative neuropathological study

BackgroundIn typical patients with multiple system atrophy with predominant parkinsonism (MSA-P) levodopa is ineffective. However, there are some of these patients who respond well to levodopa treatment. Levodopa efficacy in MSA-P patients is thought to be related to the degree of putaminal damage,...

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Bibliographic Details
Main Authors: Mitsuyoshi Tamura, Takahiro Takeda, Yoshihisa Kitayama, Tomoki Suichi, Kazumoto Shibuya, Sakurako Harada-Kagitani, Takashi Kishimoto, Satoshi Kuwabara, Shigeki Hirano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Neurology
Subjects:
multiple system atrophy
levodopa
putamen
pathology
presynaptic dopaminergic fibers
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1293732/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1293732/full

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