Triosephosphate isomerase 1 may be a risk predictor in laryngeal squamous cell carcinoma: a multi-centered study integrating bulk RNA, single-cell RNA, and protein immunohistochemistry

Triosephosphate isomerase 1 may be a risk predictor in laryngeal squamous cell carcinoma: a multi-centered study integrating bulk RNA, single-cell RNA, and protein immunohistochemistry

Abstract Background Although great progress has been made in anti-cancer therapy, the prognosis of laryngeal squamous cell carcinoma (LSCC) patients remains unsatisfied. Quantities of studies demonstrate that glycolytic reprograming is essential for the progression of cancers, where triosephosphate...

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Bibliographic Details
Main Authors: Jian-Di Li, Yi Chen, Shu-Wen Jing, Li-Ting Wang, Yu-Hong Zhou, Zhi-Su Liu, Chang Song, Da-Zhi Li, Hai-Quan Wang, Zhi-Guang Huang, Yi-Wu Dang, Gang Chen, Jia-Yuan Luo
Format: Article
Language:English
Published: BMC 2023-12-01
Series:European Journal of Medical Research
Subjects:
LSCC
TPI1
Clinicopathological significance
Tumor immune microenvironment
scRNA-seq
hdWGCNA
Online Access:https://doi.org/10.1186/s40001-023-01568-8

Internet

https://doi.org/10.1186/s40001-023-01568-8

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