Aged human mesenchymal stem cells: the duration of bone morphogenetic protein-2 stimulation determines induction or inhibition of osteogenic differentiation
Bone morphogenetic protein 2 (BMP-2) is a potent osteoinductive cytokine and a growing number of i<em>n vitro</em> studies analyze its effects on human mesenchymal stem cells (hMSC) derived from aged or osteoporotic donors. In these studies the exact quantification of osteogenic differen...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Open Medical Publishing
2014-06-01
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Series: | Orthopedic Reviews |
Subjects: | |
Online Access: | http://www.pagepress.org/journals/index.php/or/article/view/5242 |