Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury

Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury

Overexpression of long non-coding RNA, lncCIRPIL protects the heart from ischemia/reperfusion (I/R) injury. LncCIRPIL binds and sequesters p53 in the cytoplasm to exert the cardioprotective action.

Bibliographic Details
Main Authors: Yuan Jiang, Ying Yang, Yang Zhang, Jiqin Yang, Man-man Zhang, Shangxuan Li, Genlong Xue, Xingda Li, Xiaofang Zhang, Jiming Yang, Xiang Huang, Qihe Huang, Hongli Shan, Yanjie Lu, Baofeng Yang, Zhenwei Pan
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03651-y

Internet

https://doi.org/10.1038/s42003-022-03651-y

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