A COMPARATIVE CHARACTERISTIC OF ANTIGENIC PROPERTIES OF RECOMBINANT AND NATIVE HBS-ANTIGENS WITH G145R MUTATION AND EVALUATION OF THEIR IMMUNOGENICITY
Background: One of the important reasons for spreading of hepatitis B virus (HBV) under conditions of vaccine pressure is emergence of escape mutations. Prevalent G145R mutation in S-gene leads to the most expressed changes of serological properties of HBV. Consequently, HBsAg is modified so thoroug...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Central Research Institute for Epidemiology
2017-08-01
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| Series: | Вопросы вирусологии |
| Subjects: | |
| Online Access: | https://virusjour.crie.ru/jour/article/viewFile/164/74 |