Our biology working against us in obesity: A narrative review on implications for management of osteoarthritis

Obesity is the major modifiable risk factor for osteoarthritis (OA). A major focus of management in OA is weight loss. Although we live in an obesogenic environment, obesity has a predominantly genetic and epigenetic basis. This explains a person's weight set point which is defended by biologic...

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Bibliographic Details
Main Authors: Flavia M. Cicuttini, Joseph Proietto, Yuan Z. Lim
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913123000742