Preparation and Hydro-Lipophilic Properties of Monosubstituted <i>N</i>-Aryl-4-hydroxyquinoline-3-carboxanilides

Preparation and Hydro-Lipophilic Properties of Monosubstituted <i>N</i>-Aryl-4-hydroxyquinoline-3-carboxanilides

A series of twenty-two monosubstituted <i>N</i>-aryl-4-hydroxyquinoline-3-carboxanilides designed as dual anti-invasive agents was prepared and characterized. Lipophilicity significantly affects biological activities of compounds and ADME properties; therefore, the lipo-hydrophilic prope...

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Bibliographic Details
Main Authors: Tomas Gonec, Lucia Vrablova, Dominika Pindjakova, Tomas Strharsky, Michal Oravec, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Chemistry Proceedings
Subjects:
hydroxyquinoline-carboxanilides
synthesis
lipophilicity
Online Access:https://www.mdpi.com/2673-4583/12/1/28

Internet

https://www.mdpi.com/2673-4583/12/1/28

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