Molecular Docking Assessment of Cathinones as 5-HT<sub>2A</sub>R Ligands: Developing of Predictive Structure-Based Bioactive Conformations and Three-Dimensional Structure-Activity Relationships Models for Future Recognition of Abuse Drugs

Molecular Docking Assessment of Cathinones as 5-HT<sub>2A</sub>R Ligands: Developing of Predictive Structure-Based Bioactive Conformations and Three-Dimensional Structure-Activity Relationships Models for Future Recognition of Abuse Drugs

Commercially available cathinones are drugs of long-term abuse drugs whose pharmacology is fairly well understood. While their psychedelic effects are associated with 5-HT<sub>2A</sub>R, the enclosed study summarizes efforts to shed light on the pharmacodynamic profiles, not yet known at...

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Bibliographic Details
Main Authors: Nevena Tomašević, Maja Vujović, Emilija Kostić, Venkatesan Ragavendran, Biljana Arsić, Sanja Lj. Matić, Mijat Božović, Rossella Fioravanti, Eleonora Proia, Rino Ragno, Milan Mladenović
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
cathinones
5-HT<sub>2A</sub>R
molecular docking
3-D QSAR
Online Access:https://www.mdpi.com/1420-3049/28/17/6236

Internet

https://www.mdpi.com/1420-3049/28/17/6236

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