Intranasally Delivered Adenoviral Vector Protects Chickens against Newcastle Disease Virus: Vaccine Manufacturing and Stability Assessments for Liquid and Lyophilized Formulations

Intranasally Delivered Adenoviral Vector Protects Chickens against Newcastle Disease Virus: Vaccine Manufacturing and Stability Assessments for Liquid and Lyophilized Formulations

Newcastle disease (ND) remains a critical disease affecting poultry in sub-Saharan Africa. In some countries, repeated outbreaks have a major impact on local economies and food security. Recently, we developed an adenovirus-vectored vaccine encoding the Fusion protein from an Ethiopian isolate of Ne...

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Bibliographic Details
Main Authors: Omar Farnós, Barbara Cristina Martins Fernandes Paes, Belayneh Getachew, Samia Rourou, Ameni Chaabene, Esayas Gelaye, Takele A. Tefera, Amine A. Kamen
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Vaccines
Subjects:
newcastle disease virus
adenovirus vaccine
vaccine manufacturing
intranasal vaccination
mucosal protection
HEK293 suspension cells
Online Access:https://www.mdpi.com/2076-393X/12/1/41

Internet

https://www.mdpi.com/2076-393X/12/1/41

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