Genome wide nucleosome mapping for HSV-1 shows nucleosomes are deposited at preferred positions during lytic infection.
HSV is a large double stranded DNA virus, capable of causing a variety of diseases from the common cold sore to devastating encephalitis. Although DNA within the HSV virion does not contain any histone protein, within 1 h of infecting a cell and entering its nucleus the viral genome acquires some hi...
Principais autores: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2015-01-01
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coleção: | PLoS ONE |
Acesso em linha: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117471&type=printable |