Genome wide nucleosome mapping for HSV-1 shows nucleosomes are deposited at preferred positions during lytic infection.

HSV is a large double stranded DNA virus, capable of causing a variety of diseases from the common cold sore to devastating encephalitis. Although DNA within the HSV virion does not contain any histone protein, within 1 h of infecting a cell and entering its nucleus the viral genome acquires some hi...

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Detalhes bibliográficos
Principais autores: Jaewook Oh, Iryna F Sanders, Eric Z Chen, Hongzhe Li, John W Tobias, R Benjamin Isett, Sindura Penubarthi, Hao Sun, Don A Baldwin, Nigel W Fraser
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS ONE
Acesso em linha:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117471&type=printable