Analysis of f5 gene polymorphism in men with coronary atherosclerosis using whole exome sequencing

Factor V, encoded by the F5 gene, is a procoagulant blood clotting factor that increases the production of thrombin, the central enzyme that converts fibrinogen to fibrin, which leads to the formation of a blood clot. The F5 gene is localized to 1q24.2 chromosome and consists of 25 exons. There are...

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Main Authors: E. V. Striukova, E. V. Shakhtshneider, D. E. Ivanoshchuk, Yu. I. Ragino, Ya. V. Polonskaya, I. S. Murashov, A. M. Volkov, A. V. Kurguzov, A. M. Chernyavsky, E. S. Valeev, V. N. Maksimov, E. V. Kashtanova
Format: Article
Language:Russian
Published: Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2021-03-01
Series:Атеросклероз
Subjects:
Online Access:https://ateroskleroz.elpub.ru/jour/article/view/412/387