Neuroendocrine Regulation of Stress‐Induced T Cell Dysfunction during Lung Cancer Immunosurveillance via the Kisspeptin/GPR54 Signaling Pathway

Neuroendocrine Regulation of Stress‐Induced T Cell Dysfunction during Lung Cancer Immunosurveillance via the Kisspeptin/GPR54 Signaling Pathway

Abstract Emerging evidence suggests that physiological distress is highly correlated with cancer incidence and mortality. However, the mechanisms underlying psychological challenges‐mediated tumor immune evasion are not systematically explored. Here, it is demonstrated that acute restraint (AR) incr...

Full description

Bibliographic Details
Main Authors: Su Zhang, Fangfei Yu, Anran Che, Binghe Tan, Chenshen Huang, Yuxue Chen, Xiaohong Liu, Qi Huang, Wenying Zhang, Chengbin Ma, Min Qian, Mingyao Liu, Juliang Qin, Bing Du
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Advanced Science
Subjects:
ERK5
GPR54
kisspeptin
stress
T cell exhaustion
Online Access:https://doi.org/10.1002/advs.202104132

Internet

https://doi.org/10.1002/advs.202104132

Similar Items