Improving the Realism of White Matter Numerical Phantoms: A Step toward a Better Understanding of the Influence of Structural Disorders in Diffusion MRI

Improving the Realism of White Matter Numerical Phantoms: A Step toward a Better Understanding of the Influence of Structural Disorders in Diffusion MRI

White matter is composed of irregularly packed axons leading to a structural disorder in the extra-axonal space. Diffusion MRI experiments using oscillating gradient spin echo sequences have shown that the diffusivity transverse to axons in this extra-axonal space is dependent on the frequency of th...

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Bibliographic Details
Main Authors: Kévin Ginsburger, Fabrice Poupon, Justine Beaujoin, Delphine Estournet, Felix Matuschke, Jean-François Mangin, Markus Axer, Cyril Poupon
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Physics
Subjects:
diffusion time-dependence
white matter microstructure
trapezoidal OGSE sequences
axonal diameter
Monte-Carlo simulations
biomimicking numerical phantoms
Online Access:http://journal.frontiersin.org/article/10.3389/fphy.2018.00012/full

Internet

http://journal.frontiersin.org/article/10.3389/fphy.2018.00012/full

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