Synergistic interaction of hTGF-β3 with hBMP-6 promotes articular cartilage formation in chitosan scaffolds with hADSCs: implications for regenerative medicine

Abstract Background Human TGF-β3 has been used in many studies to induce genes coding for typical cartilage matrix components and accelerate chondrogenic differentiation, making it the standard constituent in most cultivation media used for the assessment of chondrogenesis associated with various st...

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Bibliographic Details
Main Authors: Yijiang Huang, Daniel Seitz, Yan Chevalier, Peter E. Müller, Volkmar Jansson, Roland M. Klar
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Biotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12896-020-00641-y