Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1

Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1

BackgroundGlioblastoma multiforme (GBM) is the most lethal brain cancer in adults, characterized by rapid growth, extensive invasiveness, and poor prognosis, and there is still a lack of effective treatments. Here, we aimed to explore the role of triptolide (TPL), purified from Tripterygium wilfordi...

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Bibliographic Details
Main Authors: Chao Yuan, Yanli Liao, Shengjie Liao, Mi Huang, Duanzhuo Li, Weibin Wu, Yi Quan, Liqiang Li, Xin Yu, Wenxia Si
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
triptolide (PubChem CID: 107985)
Glioblastoma multiforme
PROX1, apoptosis
migration and invasion
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1077640/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1077640/full

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