A methylbenzimidazole derivative regulates mammalian circadian rhythms by targeting Cryptochrome proteins [version 1; peer review: 2 approved]

Background: Impairment of the circadian clock has been associated with numerous diseases, including sleep disorders and metabolic disease. Although small-molecules that modulate clock function may form the basis of drug discovery of clock-related diseases, only a few compounds that selectively targe...

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Bibliographic Details
Main Authors: Ayato Sato, Tsuyoshi Hirota, Yoshiko Nagai, Shinsuke Inuki, Moeri Yagi, Simon Miller
Format: Article
Language:English
Published: F1000 Research Ltd 2022-09-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/11-1016/v1