JieZe-1 Alleviates HSV-2 Infection-Induced Genital Herpes in Balb/c Mice by Inhibiting Cell Apoptosis via Inducing Autophagy

JieZe-1 Alleviates HSV-2 Infection-Induced Genital Herpes in Balb/c Mice by Inhibiting Cell Apoptosis via Inducing Autophagy

Objectives: Genital herpes (GH) is a common sexually transmitted disease mainly caused by herpes simplex virus 2 (HSV-2). JieZe-1 (JZ-1) is an in-hospital prescription that has been used in Tongji Hospital for many years to treat various lower female genital tract infectious diseases. Our previous s...

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Bibliographic Details
Main Authors: Qingqing Shao, Fan Wu, Tong Liu, Wenjia Wang, Tianli Liu, Ximing Jin, Lijun Xu, Yonggui Ma, Guangying Huang, Zhuo Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
JZ-1
HSV-2 infection
genital herpes
apoptosis
autophagy
PI3K/Akt/mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.775521/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.775521/full

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