Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment

Immunotoxins (ITXs) are chimeric molecules that combine the specificity of a targeting domain, usually derived from an antibody, and the cytotoxic potency of a toxin, leading to the selective death of tumor cells. However, several issues must be addressed and optimized in order to use ITXs as therap...

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Bibliographic Details
Main Authors: Javier Narbona, Luisa Hernández-Baraza, Rubén G. Gordo, Laura Sanz, Javier Lacadena
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/7/1042