The role of synthetic ligand of PPARα in regulation of transcription of genes related to mitochondria biogenesis and dynamic in an animal model of Alzheimer’s disease

The role of synthetic ligand of PPARα in regulation of transcription of genes related to mitochondria biogenesis and dynamic in an animal model of Alzheimer’s disease

Peroxisome proliferator-activated receptors α (PPARα) are members of the nuclear receptors family and a very potent transcription factor engaged in the regulation of lipid and energy metabolism. Recent data suggest that PPARα could play an important role in the pathomechanism of Alzheimer’s disease...

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Bibliographic Details
Main Authors: Sylwia Żulińska, Anna K. Strosznajder, Joanna B. Strosznajder
Format: Article
Language:English
Published: Termedia Publishing House 2023-07-01
Series:Folia Neuropathologica
Subjects:
alzheimer’s disease
nrf2
ppara
mitochondria biogenesis
gw7647
tfam
neuroprotection
Online Access:https://www.termedia.pl/The-role-of-synthetic-ligand-of-PPAR-in-regulation-r-nof-transcription-of-genes-related-to-mitochondria-biogenesis-r-nand-dynamic-in-an-animal-model-of-Alzheimer-s-disease,20,51014,1,1.html

Internet

https://www.termedia.pl/The-role-of-synthetic-ligand-of-PPAR-in-regulation-r-nof-transcription-of-genes-related-to-mitochondria-biogenesis-r-nand-dynamic-in-an-animal-model-of-Alzheimer-s-disease,20,51014,1,1.html

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