Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection.

Progress in tuberculosis vaccine development is hampered by an incomplete understanding of the immune mechanisms that protect against infection with Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis. Although the M72/ASOE1 trial yielded encouraging results (54% efficacy in subjec...

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Bibliographic Details
Main Authors: Johannes Nemeth, Gregory S Olson, Alissa C Rothchild, Ana N Jahn, Dat Mai, Fergal J Duffy, Jared L Delahaye, Sanjay Srivatsan, Courtney R Plumlee, Kevin B Urdahl, Elizabeth S Gold, Alan Aderem, Alan H Diercks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008655