Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial‐mesenchymal transition via Hedgehog signaling pathway

Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial‐mesenchymal transition via Hedgehog signaling pathway

Abstract Background Based on previous findings, we hypothesized that Vasohibin 2 (VASH2) protein may induce epithelial‐mesenchymal transition (EMT) of pancreatic cancer (PC) cells by promoting the malignant behaviors of these cells. The present study aimed to test this hypothesis and explore the pos...

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Bibliographic Details
Main Authors: Ye Zhang, Xiaofeng Xue, Xiaoqian Zhao, Lei Qin, Yu Shen, Huiqiang Dou, Jialin Sun, Tong Wang, Da‐Qing Yang
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Cancer Medicine
Subjects:
epithelial‐mesenchymal transition
Hedgehog signaling
pancreatic cancer
VASH2
ZEB1/2
Online Access:https://doi.org/10.1002/cam4.1752

Internet

https://doi.org/10.1002/cam4.1752

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