Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity

Abstract SulE, an esterase, which detoxifies a variety of sulfonylurea herbicides through de-esterification, provides an attractive approach to remove environmental sulfonylurea herbicides and develop herbicide-tolerant crops. Here, we determined the crystal structures of SulE and an activity improv...

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Bibliographic Details
Main Authors: Bin Liu, Weiwu Wang, Jiguo Qiu, Xing Huang, Shenshen Qiu, Yixuan Bao, Siqiong Xu, Luyao Ruan, Tingting Ran, Jian He
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40103-5