Synthesis and Pharmacological Evaluation of Novel Phenyl Sulfonamide Derivatives Designed as Modulators of Pulmonary Inflammatory Response

In this paper we report the design, synthesis and pharmacological evaluation of a new series of phenyl sulfonamide derivatives 2a–h and 3–8 planned by structural modification on the anti-inflammatory prototype LASSBio-468 (1). Among the synthesized analogues, the tetraflu...

Full description

Bibliographic Details
Main Authors: Lídia Moreira Lima, Eliezer J. Barreiro, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva, Thiago José Figueira Ramos, Ana Carolina Santos de Arantes, Maria Letícia de Castro Barbosa
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/12/14651