Tumour Angiogenesis in Uveal Melanoma Is Related to Genetic Evolution

Tumour Angiogenesis in Uveal Melanoma Is Related to Genetic Evolution

Increased angiogenesis is associated with a higher metastasis- and mortality rate in uveal melanoma (UM). Recently, it was demonstrated that genetic events, such as 8q-gain and BAP1-loss, influence the level of immune infiltrate. We aimed to determine whether genetic events, and specific cytokines,...

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Bibliographic Details
Main Authors: Niels J. Brouwer, Gülçin Gezgin, Annemijn P.A. Wierenga, Inge H.G. Bronkhorst, Marina Marinkovic, Gregorius P.M. Luyten, Mieke Versluis, Wilma G.M. Kroes, Pieter A. van der Velden, Robert M. Verdijk, Martine J. Jager
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
uveal melanoma
angiogenesis
oncology
BAP1
VEGF-B
chromosomes
macrophages
Online Access:https://www.mdpi.com/2072-6694/11/7/979

Internet

https://www.mdpi.com/2072-6694/11/7/979

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