Metformin improves cognitive impairment in patients with schizophrenia: associated with enhanced functional connectivity of dorsolateral prefrontal cortex

Abstract Cognitive impairment is a core feature of schizophrenia, which is aggravated by antipsychotics-induced metabolic disturbance and lacks effective pharmacologic treatments in clinical practice. Our previous study demonstrated the efficiency of metformin in alleviating metabolic disturbance fo...

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Bibliographic Details
Main Authors: Tiannan Shao, Jing Huang, Yuxin Zhao, Weiyan Wang, Xiaohan Tian, Gangrui Hei, Dongyu Kang, Yong Gao, Fangkun Liu, Jingping Zhao, Bing Liu, Ti-Fei Yuan, Renrong Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02616-x