Metformin improves cognitive impairment in patients with schizophrenia: associated with enhanced functional connectivity of dorsolateral prefrontal cortex
Abstract Cognitive impairment is a core feature of schizophrenia, which is aggravated by antipsychotics-induced metabolic disturbance and lacks effective pharmacologic treatments in clinical practice. Our previous study demonstrated the efficiency of metformin in alleviating metabolic disturbance fo...
Main Authors: | Tiannan Shao, Jing Huang, Yuxin Zhao, Weiyan Wang, Xiaohan Tian, Gangrui Hei, Dongyu Kang, Yong Gao, Fangkun Liu, Jingping Zhao, Bing Liu, Ti-Fei Yuan, Renrong Wu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-10-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-023-02616-x |
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