Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration

Abstract Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal neurons, which causes disabling motor disorders. Scientific findings support the role of epigenetics mechanism in the development and progression of many neurodegenerative diseases, including PD. In...

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Bibliographic Details
Main Authors: Deborah Mannino, Sarah Adriana Scuderi, Giovanna Casili, Valentina Bova, Laura Cucinotta, Marika Lanza, Alessia Filippone, Emanuela Esposito, Irene Paterniti
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-023-02842-6