ABC transporters in CSCs membranes as a novel target for treating tumour relapse

ABC transporters in CSCs membranes as a novel target for treating tumour relapse

CSCs are responsible for the high rate of recurrence and chemoresistance of different type of cancers. The current antineoplastic agents, able to inhibit bulk replicating cancer cells and radiation treatment, were found inefficacious towards CSCs since this subpopulation has several intrinsic mechan...

Full description

Bibliographic Details
Main Authors: LAURA eZINZI, Marialessandra eContino, Mariangela eCantore, Elena eCapparelli, Marcello eLeopoldo, Nicola Antonio Colabufo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Pharmacology
Subjects:
HTS
MDR
CSCs
TICs markers
P-gp.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00163/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00163/full

Similar Items