Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors

Triple-negative breast cancer (TNBC) is a type of breast tumor that currently lacks options for targeted therapy. Tremendous effort has been made to identify treatment targets for TNBC. Here, we report that the expression level of anaphase promoting complex (APC) coactivator Cdh1 in TNBC is elevated...

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Bibliographic Details
Main Authors: Junjun Li, Mengjiao Lan, Jin Peng, Qunli Xiong, Yongfeng Xu, Yang Yang, Ying Zhou, Jinlu Liu, Zhu Zeng, Xiaojuan Yang, Zhiwei Zhang, Pumin Zhang, Qing Zhu, Wei Wu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/5/803