The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model

The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model

(1) Background: Chronic venous insufficiency (CVI) is a common disorder related to functional and morphological abnormalities of the venous system. Inflammatory processes and angiogenesis alterations greatly concur to the onset of varicose vein. KYP-2047 is a selective inhibitor of prolyl oligopepti...

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Bibliographic Details
Main Authors: Giovanna Casili, Marika Lanza, Sarah Adriana Scuderi, Salvatore Messina, Irene Paterniti, Michela Campolo, Emanuela Esposito
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
chronic venous insufficiency
prolyl oligopeptidase (POP)
inflammation
angiogenesis
endothelial disfunction
Online Access:https://www.mdpi.com/2227-9059/8/12/604

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https://www.mdpi.com/2227-9059/8/12/604

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