Comparative Infections of Zika, Dengue, and Yellow Fever Viruses in Human Cytotrophoblast-Derived Cells Suggest a Gating Role for the Cytotrophoblast in Zika Virus Placental Invasion

ABSTRACT The Zika virus (ZIKV) is teratogenic and considered a TORCH pathogen (toxoplasmosis [Toxoplasma gondii], rubella, cytomegalovirus, herpes simplex virus [HSV], and other microorganisms capable of crossing the blood-placenta barrier). In contrast, the related flavivirus dengue virus (DENV) an...

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Main Authors: Mercedes Viettri, Gerson Caraballo, Maria Elena Sanchez, Aurora Espejel-Nuñez, Abigail Betanzos, Vianney Ortiz-Navarrete, Guadalupe Estrada-Gutierrez, Porfirio Nava, Juan E. Ludert
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00630-23